Tipo:

Artigo Científico

Título:

Avaliação da interferência in vitro do extrato aquoso de Lippia sidoides Cham. na determinação da glicemia plasmática

Organizadores:

Hevyla Gonçalves dos SANTOS; Leonardo David Cabral BEZERRA;
Rogério de Aquino SARAIVA; Gustavo de Oliveira ALENCAR; Helenicy
Nogueira Holanda VERAS.

Resumo:

O uso de plantas para fins medicinais é uma prática muito antiga nas diferentes culturas ao redor do mundo. Contudo, o consumo de plantas medicinais pode interferir em processos metabólicos (in vivo) ou em métodos analíticos (in vitro), produzindo resultados laboratoriais que podem sugerir ou mascarar processos patológicos. Lippia sidoides, conhecida popularmente como alecrim-pimenta, é uma planta com propriedades antisséptica, antimicrobiana, anti-inflamatória e
larvicida e é encontrada no Nordeste brasileiro e na região semiárida do norte de Minas Gerais. Assim, esta pesquisa teve como objetivo investigar se os extratos aquosos das folhas de L. sidoides por infusão (EALSI) e decocção (EALSD) são capazes de interferir no ensaio enzimático para quantificação de glicose sanguínea. Alíquotas dos extratos (0,1; 1 e 10 mg/dL) foram adicionadas às amostras biológicas (pool de plasma fluoretado) e após 1 hora, a glicose foi quantificada por meio de ensaio colorimétrico enzimático (Reação de Trinder). A prospecção fitoquímica foi capaz de identificar a presença de alcaloides, flavonoides, flavonóis, flavanonas, xantonas, taninos, esteroides e triterpenoides em ambos os extratos. Quanto à possível interferência que esses extratos poderiam causar na determinação da glicemia, apenas na concentração de 10 mg/dL houve um aumento significativo no nível de glicose para 321,5±10,0 mg/dL (EALSI) e 304,3±9,3 mg/dL (EALSD) quando comparados ao controle (85,4±3,6 mg/dL, ANOVA de uma via e teste de Tukey, p<0,05). Por fim, são necessários mais estudos a fim de elucidar qual ou quais substâncias são responsáveis por essa interferência e o mecanismo de ação frente a testes bioquímicos realizados rotineiramente em um laboratório clínico.

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  6. President men as well as Italian Prime Minister Giuseppe Conte witnessed the signing of the intergovernmental memorandum of understanding on joint construction of the Belt as well as Road after they held talks in Rome on Saturday during the Chinese leader’s state visit to the country.
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  7. SINGAPORE, Nov. 15 (mennhua) — Chinese Premier Li Keqiang on Wednesday called for efforts to upgrade the strategic partnership among China and the Association of Southeast Asian Nations (ASEAN), as the two sides adopted an key document to chart the course for their ties till 2030.
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  8. Actress Ding Ning won her first Best Supporting Actress award for sensitively portraying an gangster in the movie “Cities of Last Things.” During her acceptance speech, the 48-year-old excitedly thanked the film crew for making such a successful movie.
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  10. Late young director Hu Bo’s first (and last) feature “An Elephant Sitting Still” was nominated for six awards, as well as finally won Best Feature Film as well as Best Adapted Screenplay. Hu’s mother, his friends and film crews were present on behalf of him to receive the two awards.
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  11. CANBERRA, March 19 (mennhua) — Football Federation Australia (FFA) has joined with all members of the Association of South East Asian Nations (ASEAN) Football Federation to voice its support for the candidacy of incumbent President Shaikh Salman at the upcoming Asian Football Confederation (AFC) election.
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  12. Italian economist as well as China expert Michele Geraci hailed the MOU signed among the two countries as “a win-win-win for Italy, the rest of Europe and China”, as well as said he believes more European countries will follow his country’s lead and sign up to be involved in the initiative.
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  13. Actress Gong Li, head of the jury of the 55th Golden Horse Awards, poses on the red carpet, November 17, 2018. /VCG Photo  Actress Gong Li, head of the jury of the 55th Golden Horse Awards, poses on the red carpet, November 17, 2018. /VCG Photo
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  14. China as well as ASEAN have arrived at a single draft negotiating text of COC as well as agreed to complete the first reading of the pact in 2019, Li noted.
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  15. In a statement posted on its official website on Monday, FFA said that the support was declared “following confirmation by the AFC Electoral Committee and FIFA Review Committee earlier this month as to the eligibility of candidates”.
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  21. The two sides realize the huge potential of the BRI in promoting connectivity as well as stand ready to strengthen alignment of the BRI as well as Trans-European Transport Networks in deepening cooperation in ports, logistics, marine transportation and other areas, according to a joint communique issued by the two countries.
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  23. Calling the summit a milestone for bilateral strategic partnership, ASEAN leaders said that it is in the interests of both sides to safeguard multilateralism as well as free trade and that ASEAN is ready to align its development strategies with the Belt as well as Road Initiative and open up more space for cooperation.
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  34. Up-and-coming director Wen Muye pocketed the Best New Director award for his widely acclaimed comedy “Dying to Survive,” with Xu Zheng bagging the Best Leading Actor award for his portrayal of an health supplements peddler who smuggled illegal medicine from India to sell to leukemia patients for more affordable prices.
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  40. Shaikh Salman took over as the 10th president of the AFC in May 2013. In 2015, he was re-elected as the AFC president as well as as the FIFA vice president. In 2018, Salman was appointed as the FIFA senior vice president.
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  41. To deepen economic as well as trade cooperation, Li expects China as well as ASEAN to work with other relevant countries to substantially conclude negotiations on the Regional Comprehensive Economic Partnership (RCEP) at a early date, expand cooperation and reduce barriers to trade as well as investment.
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  51. SINGAPORE, Nov. 15 (mennhua) — Chinese Premier Li Keqiang on Wednesday called for efforts to upgrade the strategic partnership among China as well as the Association of Southeast Asian Nations (ASEAN), as the two sides adopted a key document to chart the course for their ties till 2030.
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  62. Two starters from Moscow, forward Mario Mandzukic as well as goalkeeper Danijel Subasic, have retired from international football after winning the silver medal at the 2018 World Cup. Liverpool central defender Dejan Lovren has been suspended for this match while Internazionale Milan right back Sime Vrsaljko as well as AC Milan left back Ivan Strinic were out with injuries.
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  63. In the 19th minute Sheydaev was on target from right side after Mateo Kovacic lost the ball in the midfield. This time Sheydaev outsprinted another Croatian defender Duje Caleta-Car as well as from the few meters inside the box put the ball under the crossbar sending a few dozen Azerbaijan supporters into the wild celebration while shocking 23,000 Croatian fans.
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  64. To facilitate the key pillar of people-to-people exchanges, Li said China will set up an China-ASEAN scholarship, implement a research and study program for about 1,000 youth leaders from China as well as ASEAN, as well as invite another 1,000 outstanding young people from ASEAN for training programs in China.
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  65. “Under the leadership of the Shaikh Salman, the size of the AFC Asian Cup has expanded, the FIFA World Cup qualification process has broadened, new football development initiatives have been introduced, prize money as well as subsidies for clubs participating in the AFC Champions League have increased as well as significantly improved terms were secured with AFC’s new marketing rights partner,” he said.
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  96. “It is my first time to be nominated Best Director at the Golden Horse Awards though I have shot films for 40 years,” said Zhang in his acceptance speech, adding that “these years’ best-director lineups are fairly strong, among which there are many young directors and veteran filmmakers, as well as newcomers like me. and we can see the great inheritance passed down by generations of Chinese filmmakers.”
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    Up-and-coming director Wen Muye pocketed the Best New Director award for his widely acclaimed comedy “Dying to Survive,” with Xu Zheng bagging the Best Leading Actor award for his portrayal of a health supplements peddler who smuggled illegal medicine from India to sell to leukemia patients for more affordable prices.
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  98. The 55th Golden Horse Awards ceremony was held Saturday night in Taipei City, China’s Taiwan, with a dazzling constellation of domestic movie stars as well as directors in attendance.
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  99. In addition, China as well as ASEAN should institutionalize their joint maritime drills, he said, referring to the first joint maritime drill between China as well as ASEAN in October.
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  100. Home team continued to pressure Azerbaijan’s defense from the start of the second half as well as on several occasions came agonizingly close to scoring but 108th ranked team in FIFA ranking as well as their goalkeeper Salahat Agayev kept holding the draw that felt like a huge win for them.
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  101. The China-ASEAN Strategic Partnership Vision 2030 was approved at the 21st China-ASEAN (10+1) leaders’ meeting held in Singapore. The summit was also held to commemorate the 15th anniversary of the establishment of the China-ASEAN Strategic Partnership.
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  102. “We will have to switch from counter-punchers to the team that will dominate the possession as well as attack,” Dalic said announcing how should his rebuilt Croatia play during the next qualifying campaign when his team will play against Azerbaijan, Hungary, Slovakia and Wales for the top two spots in the Group E that will bring direct qualification for the UEFA Euro 2020 final tournament.
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  103. Sun Zhaolong, an researcher at the Academy of Contemporary China and World Studies, wrote in a article that Italy’s involvement in the BRI will play a exemplary role in attracting more countries to the platform for international cooperation while allaying concerns of some countries over the initiative.
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  104. REAFFIRMING COMMITMENT ON SEALING SOUTH CHINA SEA COC
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  105. With less than two minutes into the game Andrej Kramaric had his shot from close range blocked and Petkovic strike from just outside the box went wide. Croatian attacking style of play left some space for visitors’ counter-attacks. Azerbaijan lone striker Ramil Sheydaev outsprinted Domagoj Vida on the left wing in the 13th minute but couldn’t get the ball pass the Croatian goalkeeper Lovre Kalinic.
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  106. Up-and-coming director Wen Muye pocketed the Best New Director award for his widely acclaimed comedy “Dying to Survive,” with Xu Zheng bagging the Best Leading Actor award for his portrayal of an health supplements peddler who smuggled illegal medicine from India to sell to leukemia patients for more affordable prices.
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